Diane Yvonne Brown, 17, who attended Friendly Senior High School in Oxon Hill, where she had lived with her family for the past 10 years, died of aplastic anemia Sunday at the Southern Maryland Hospital Center in Clinton.

Miss Brown, who was born in Philadelphia, attended schools in Pennsylvania before moving to this area in 1971. She attended Harmony Hall Elementary School in Oxon Hill and Eugene Burroughs Junior High School in Accokeek, Md. She would have been a senior at Friendly Senior High this semester. She was cocaptain of the Friendly High School Drill Team.

She participated in sports sponsored by the Fort Washington Recreation Council and was a recreational leader for the Maryland-National Capital Park & Planning Commission, where she worked with children. She was a member of the Youth Medical Society and Girl Scouts of America.

Survivors include her parents, Carl A. and Kathleen Smith Brown, and a brother, Michael E., all of Oxon Hill; two other brothers, Carl A. Jr., of Salisbury, Md., and William, of Japan, and her grandmothers, Rebecca Smith, and Louise West, both of Philadelphia.

The family suggests that expressions of sympathy be in the form of contributions to the Diane Brown Memorial Fund for Research in Aplastic Anemia, c/o The Committee of Friends, Johns Hopkins University, Baltimore.