Margot Pinkett Dyson, 65, vice president and office manager of John R. Pinkett Inc., a Washington firm of real estate and insurance agents and brokers, died Monday at her home in Washington after a stroke.

Mrs. Dyson was born in St. Louis and reared in Atlanta and Washington. She graduated from Dunbar High School in 1931 and earned a bachelor's degree in home economics from Howard University in 1936.

She served an internship in dietetics at Freedmen's Hospital, now Howard University Hospital, and worked as a dietitian at hospitals in Nashville and Philadelphia before her marriage in 1940 to Dr. Albert Homer Dyson Jr., a Cleveland physician.

She lived in Washington during World War II, while her husband was serving in the Army Medical Corps.

After her husband's death in 1948, Mrs. Dyson returned to Washington and joined John R. Pinkett Inc.

Active in civic, professional and community organizations, she was a founder of the Baker's Dozen Youth Center here and a member of the League of Women Voters.

She also was a member of the NAACP of Cleveland.

Survivors include a daughter, Margot D. Ferguson; a son, Albert H. III; three sisters, Flaxie M. Pinkett, Frances P. Roberson and Charlotte P. Dodson, and a brother, Charles C. Pinkett, all of Washington, and two grandchildren.