Dr. Russell Lee Hughes, 50, a physician who specialized in radiology, died Tuesday at his home in Great Falls, Va. He had a heart ailment.

Dr. Hughes, who was born in Roanoke, graduated from Roanoke College. He earned his medical degree at the Medical College of Virginia and did his internship at Philadelphia General Hospital.

After service as an Army captain in the Panama Canal Zone, he completed a residency in radiology at the old Doctors Hospital in Washington. He then joined the firm of Goover, Christie and Merritt, specialists in radiology with offices in Washington and Chevy Chase. He remained there until his death.

Dr. Hughes was the senior attending physician in radiology at Sibley Memorial Hospital and the vice chairman of its radiology department.

He was a diplomate of the American Board of Radiology and a member of several other professional organizations. He was the author of many papers in his field.

He was a member of the River Bend Country Club and the parish of St. Catherine of Siena Catholic Church in Great Falls.

Survivors include his wife, Josephine DiBella Hughes, and three children, Joanna, Russell and John, all of Great Falls; a brother, Claude Fitzpatrick Hughes of Abbyville, S.C., and two sisters, Jean Johnson of Salem, Va., and Martha Wimmer of Burlington, N.C.