Maenylie M. Reed, 51, an executive officer with the Office of the Secretary of Education who was active in community affairs, died of cancer Friday at the Washington Hospital Center. She lived in Washington.

Mrs. Reed was born in Chester, S.C., and reared in Washington. She was a graduate of Armstrong High School. She joined the old U.S. Office of Education in 1961 as a statistical clerk.

She was a volunteer for the House of Ruth in Washington and a member of the D.C. Congress of Parents and Teachers, the National Association of Negro Women, and Blacks in Government, Inc. She also was a member of the Mt. Airy Baptist Church for 31 years.

She was a past president of the Young Women's League of Washington, a former matron of Miriam Chapter No. 4 of the Order of the Eastern Star and a member of the board of the Acacia Masonic Hall.

Mrs. Reed received an Outstanding Minority Participant Award from President Johnson for her work during the White House Conference on Education in 1966.

Survivors include her husband, Preston Reed Jr., and a son, Kenneth J., both of Washington; her mother, Ozellar McCluney of Cheverly; three brothers, William McCluney of Washington, and James and Ronald McCluney, both of Cheverly, and two sisters, Olalee Williams of Washington, and Juanita Griffin of Buford, Ga.