Dr. William F. Kellow, 59, dean emeritus of Jefferson Medical College in Philadelphia and one of the nation's foremost medical educators, died of cancer Thursday at his home in Wynnewood, Pa.

Dr. Kellow was dean and vice president of the college from 1967 until his retirement last month.

During his 34-year career, he held several key medical education positions with the American Medical Association and was a member of its Committee on Medical Education, the accreditation body for U.S. and Canadian medical schools.

Dr. Kellow was born in Geneva, N.Y., and graduated from the University of Notre Dame. He earned a medical degree from Georgetown University's School of Medicine and served as an intern and resident physician at D.C. General and Georgetown University hospitals.

From 1947 to 1953, he was a clinical instructor in surgery and medicine at Georgetown.

In the late 1950s, while associate dean of the University of Illinois College of Medicine, Dr. Kellow was instrumental in establishing this country's first Office of Medical Education.

In 1977, he received the prestigious Mastership Award of the American College of Physicians.

Survivors include his wife, the former Stella Toczylowski, and five daughters, Suzanne K. Portfolio, and Joanne, Jennifer, Mary Jeanne and Kathleen Kellow; his mother, Mrs. Robert Kellow of Geneva, and a grandson.