Gladys A. Harrison, 89, a former official of the National League of Women Voters and a retired government lawyer, died of sepsis Jan. 14 at the Wisconsin Avenue Nursing Home. She lived in Washington.

Miss Harrison began her career as a government lawyer with the Agricultural Adjustment Administration in Washington in 1933. She also worked for the Puerto Rico Reconstuction Administration and the old Social Security Board. She was assistant general counsel of the Department of Health, Education and Welfare's public health division when she retired in 1958.

During her 15 years with HEW and its predecessor agencies, she also served as the department's patent officer and as president of a government conference on administrative procedure.

After leaving the government, she was elected first vice president of the Group Health Association and was a member of a judicial conference on mental disorders. She was a member of the American Civil Liberties Union and the National Democratic Woman's Club.

Miss Harrison was a native of Minneapolis and earned bachelor's and master's degrees at the University of Minnesota. She was a 1932 graduate of Yale University's law school, where she was a member of the law review. She served with the American Red Cross in France during World War I.

She leaves no immediate survivors.