The federal government has decided to retry a suspended Food and Drug Administration doctor and a leading advocate of the drug DMSO on conspiracy and corruption charges after the first trial ended last week in a hung jury.

The decision to retry Dr. K.C. Pani, of the FDA, and Dr. Stanley Jacob, promoter of the drug Pani was responsible for regulating, came after prosecutors learned that all but two members of the deadlocked jury favored conviction, according to assistant U.S. attorney James Rothschild.

Jacob lent Pani $36,500 between 1974 and 1979, allegedly to influence his official actions on DMSO.

The Coast Guard closed the Chesapeake and Delaware Canal to commercial traffic yesterday after a barge carrying a toxic industrial chemical collided with a freighter and began leaking small amounts of its 290,000-gallon cargo.

"As long as the barge is there and the chemical is there, it is a potential hazard," said Coast Guard spokesman Mike Waller in Baltimore.

The canal, which allows ships to travel between Baltimore and Philadelphia without sailing the Atlantic, was closed indefinitely to commercial traffic, but pleasure craft were being allowed through, he said.

The barge was carrying phenol, which can be fatal to marine life but posed no danger to residents because it was leaking in small amounts, officials said.