Dr. Pearl B. Holly, 73, a hematologist and psychiatrist who practiced medicine in Washington and taught at George Washington University's medical school for more than 40 years, died June 2 in a hospital in Santa Fe, N.M., after a heart attack. She maintained homes in Santa Fe and Washington.

She joined the faculty at George Washington University's medical school in 1940, and during the next 15 years taught courses in hematology and served as a chairman of the hematology department. In 1965, she began a three year psychiatric residency. Between 1968 and earlier this year, she practiced psychiatry in Washington. She was named a professor of psychiatry at George Washington University in 1970.

Dr. Holly was a native of New York City and a graduate of Hunter College. She earned master's and medical degrees at New York University. She moved here in 1938 to serve her internship at the old Gallinger Hospital. She also received training in pathology at George Washington University Hospital and in hematology at Johns Hopkins Hospital.

Her husband, George Bronz, died in 1976. Dr. Holly used her maiden name for professional purposes.

Survivors include a daughter, Elizabeth Bronz Lifschitz of San Antonio, Tex.; a brother, Harry Holly of Tamarac, Fla.; a sister, Mina Keenan of New York City, and three grandchildren.