It has been six days since Delia Raskin Goldin, a 52-year-old senior editor at the Pan American Health Organization, climbed into her gray Honda after work, waved goodbye to the garage attendant and disappeared.

Goldin was supposedly headed to her family's Alexandria apartment, where she had arranged to have dinner Wednesday with her youngest son Jack, 27, who had just returned that afternoon from Argentina.

Although friends and family said she had recently been depressed over her job and had suffered a loss of self-confidence, she gave them no reason to be concerned. "It's very unusual behavior -- that's why it's so disconcerting," said the eldest of her three children, Javier, 28.

Alexandria police said yesterday they did not suspect foul play in Goldin's disappearance but had no clues as to her whereabouts. Police described her as 5 foot, 6 inches tall, 140 pounds, with light brown hair and green eyes. She was last seen wearing a red dress. Her car, a 1983 Accord, has Virginia plates MXB 658 and a green parking sticker that reads "PAHO/WHO."

Those who know Goldin, an Argentine citizen, describe her as shy. "She's not the type that goes around making friends with everything type-of-thing," said one colleague. He described her as "a lady," and said that was her nickname, too: "Lady."

The same colleague said Goldin was not adventurous, traveling mostly between her office in Northwest Washington and her Alexandria home, where she lived with her husband, Rafael. "She's not the type of person that would take off and rent a room at the beach," the colleague said.

Goldin has been employed at the Pan American Health Organization, a regional office of the World Health Organization, for 13 years.