Four homicides occurred in the District over the holiday weekend, and arrests have been made in two of them, D.C. police said yesterday.

Two of the slayings were on Memorial Day, when an unidentified man was fatally wounded in the 5300 block of Georgia Avenue NW shortly after midnight, and another man was found shot in the head in the 3100 block of Fort Lincoln Drive NE about 8:30 a.m.

About 2 a.m. Sunday, Timothy Brandon, 32, was found in the 1500 block of Seventh Street NW, suffering from gunshot and stab wounds, and was pronounced dead at the D.C. Medical Examiner's Office about an hour later, police said.

Police said a 17-year-old from the District has been arrested and charged with second-degree murder in connection with Brandon's murder. The suspect is being charged as a juvenile.

About 11:30 p.m. Friday, Anthony Jerome Lowery, 19, of 1310 Sixth St. NW, was found suffering from stab wounds in the 800 block of L Street NW. He died at Howard University Hospital about 12:40 a.m. Saturday.

Stephon Miller Jenkins, 18, of 1220 12th St. NW, turned himself in to the D.C. police department's homicide branch about 3 p.m. Saturday and has been charged with first-degree murder in connection with Lowery's death.

In the Memorial Day homicides, a man was found shot in the chest in front of a nightclub in the 5300 block of Georgia Ave. NW about 12:20 a.m. He was taken to Washington Hospital Center, where he was pronounced dead at 4:37 a.m, police said.

Police said the victim apparently was shot by someone he argued with in the nightclub. There are no suspects, they said.

In the other homicide, the unidentified man found shot twice in the head on Fort Lincoln Drive, police said there are no suspects and they haven't determined a motive.

There have been 185 homicides in the District this year, compared to 189 at the same time last year, police said.