A 22-year-old woman died yesterday after being shot in her Northeast Washington home, allegedly by her brother. It was the first of two killings that brought the District's homicide total for the year to 394.

The woman, who lived with family members in the 300 block of 51st Street, was pronounced dead about 6 p.m. after surgery at D.C. General Hospital. Police were withholding her name last night.

Officials said they arrested the woman's brother, whom they also declined to identify, and charged him with second-degree murder in the woman's death.

"All I know is that somebody came running out and said to call an ambulance," said a neighbor. "Nothing like this has ever happened this close to here . . . . It's like a dream, you know, like it's not really happening."

A few hours after that killing, a man was found shot to death in an alley in the 5700 block of East Capitol Street SE. Officers said the man, who was not identified, was killed about 8:30 p.m. near an apartment building, and that three people were seen running from the scene.

Meanwhile, D.C. police released the names of two men found slain during the weekend.

About 10 p.m. Sunday, officers found the body of Lenard M. Payton in the rear of the 1100 block of 10th Street NW. Payton, who had no fixed address, had suffered wounds to his upper body, police said.

The body of James Jacob Richardson, 41, was found at 1:20 a.m. Saturday in front of a home in the 1000 block of 12th Street SE, a police spokesman said. Richardson, who had been shot, was pronounced dead at the Office of the D.C. Medical Examiner. Police said they had no suspects in the two weekend homicides.