Two D.C. men and a woman were charged with murder over the weekend after a Fauquier County man was gunned down near a Warrenton motel Saturday and the three suspects led police on a noontime chase on Interstate 66, authorities said.

Fatally shot was Terry Leon Tyler, 29, of Bealeton, police said. Tyler's was the second homicide this year in Fauquier County, according to authorities.

First-degree murder charges were filed late Saturday by Fauquier County authorities against Frederick E. Lucas, 25, of Half Street SW, and James E. Reid, 19, and Katrina G. Brookins, 29, both of Mountain View Place SE. They also were charged with use of a firearm in the commission of a murder, the Fauquier County Sheriff's Department said.

The three are being held without bond in the Fauquier County jail and are scheduled to appear in court Thursday.

A woman who was with the three suspects was not charged, authorities said.

At least seven Virginia State Police cars, one Fairfax County police unit and a Virginia Department of Transportation motorist-assistance patrol truck were involved in the I-66 chase Saturday, which began around the Route 50 interchange and ended at Nutley Street. The car containing the suspects raced through heavy traffic at speeds up to 75 mph. A handgun and bullets were tossed out the windows before the suspects surrendered, authorities said.

A shotgun and a second handgun were discovered in the car after the chase, police said.

Tyler was shot repeatedly by two men on an embankment near a motel service road on Route 29 just outside Warrenton, witnesses told sheriff's deputies. Authorities said they believe Tyler knew his assailants. Sheriff's Capt. C.F. Pfeiff said neither drugs nor domestic relations were involved, but he would not disclose Tyler's relationship to the suspects. The investigation is continuing, he said.

"The motive appears to be personal," Pfeiff said.

The chase began within minutes of the shooting, Pfeiff said.

A witness telephoned a description of the getaway car--a 1995 Honda with Maryland license plates owned by one of the suspects--to Fauquier County dispatchers, who flashed the information to highway police.

A VDOT safety patrol service employee monitoring his radio about 15 miles away spotted the car at 11:50 a.m. and began trailing it cautiously on I-66 in his blaze-orange truck.

State and county officers converged, and the suspects attempted to flee, state police Sgt. H.M. Chapman said.

"When the trooper activated his emergency equipment to pull the vehicle over, the occupants then began throwing stuff out of the vehicle," Pfeiff said.