New York State Democrats lost a candidate for lieutenant governor yesterday and Republicans landed one in a series of political announcements that added new confusion to Democratic Gov. Hugh Carey's effort to win reelection this year.

Just one hour after Carey made the long-expected announcement that he would run for a second term this year, his lieutenant governor, Mary Anne Krupsak, made the unexpected declaration that she would not run with him for reelection.

Krupsak coupled her withdrawal with a blast at Carey, saying he had ignored her and failed to fulfill his promise to give her a say in administration decisions.

"I have served with the governor with dedication, integrity and loyalty," she added."I had expected the same dedication from the governor . . . This quality I have found lacking."

Krupsak said she had not yet decided whether she would support Carey, who is unopposed in the Sept. 12 Democratic primary, for reelection. She indicated she is not certain what, if any, office she might run for this year.

On the Republican side, meanwhile, all was harmony as Rep. Bruce Caputo, a first-term congressman from the suburbs north of New York City, announced that he will give up his House seat to run for lieutenant governor on a ticket with Perry Duryea, who is unopposed for the GOP gubernatorial nomination.

The 34-year-old Caputo has become a well-known freshman in Congress over the past 18 months through his service on the committee investigating the Korean influence-buying scandal. Caputo pushed hard to make the probe as broad as it could be, and criticized House colleagues for what he said was a lack of zeal to pursue the case.

The Republicans say their polls show that Carey is vulnerable this year. Yesterday's events could exacerbate the incumbent's troubles.

Krupsak's withdrawal will embarass the governor, and Caputo's candidacy poses a political dilemma in light of the complicated ethnic and gender balancing that is traditional in New York. Carey must now decide whether to seek an Italian-American running-mate, to offset Caputo's attraction to that significant body of voters, or whether to recruit a female candidate, regardless of nationality, to replace Krupsak.