Members of the Democratic National Committee will be asked this week to consider substantial changes in the party's quadrennial midterm conference, beginning with the one scheduled for 1982, DNC official Robert Neuman said yesterday.

Neuman said a resolution incorporating the proposed changes is to be sent this week to the 372-member committee. It is scheduled for a vote at a meeting of the full DNC June 5 in Denver.

The proposed changes, the result of a series of recommendations by a task force headed by a party vice chairman Lynn Cutler, would change the date of the midterm conference to the spring or summer of 1982, before that year's congressional elections, rather than holding the conference in December as in the past.

The resolution also would slash the number of delegates to the conference by about 50 percent and radically change the delegate selection process. Under existing procedures, a majority of conference delegates are chosen at party caucuses at the congressional district level.

Under the proposed changes, all DNC members automatically would be delegates to the conference. Democratic state central committees in each state would choose another bloc of delegates equal in size to the DNC membership. The DNC also would elect 100 at-large delegates to assure adequate representation of minorities and women at the midterm conference.

Neuman said there appears to be a broad consensus for advancing the date of the conference before the 1982 congressional elections. He also said there has been no strong objection to the other proposed changes, which would make the conference not only smaller but also less expensive.