President Reagan refused yesterday to "comment . . . either way" on a report that he has approved a broad plan of covert political and paramilitary operations against the Cuban presence in Nicaragua.

As he stepped off the helicopter on the South Lawn of the White House on return from Camp David yesterday, the president was asked if the United States is supporting guerrilla action against Cuban intervention in Latin America, as was reported in Sunday's editions of The Washington Post.

"This is something I couldn't comment on either way," he said.

It was reported that the president appeared annoyed at the detailed information in the story. Asked whether The Post report was correct, the president said:

"All I can think that they must be talking about is what we have all called and what we have talked about many times before is this Caribbean program in which Canada, Mexico, Venezuela and the United States . . . are going to help them with their economy."

Asked about possible military involvement in the region, Reagan said, "I've heard all of that. I think sometimes you want to start an investigation of unnamed White House sources."

White House press officers also refused to comment on the report, and Secretary of State Alexander M. Haig Jr. ducked a question on the subject yesterday in an appearance on "This Week with David Brinkley" (ABC, WJLA).