Career diplomats are up in arms over Foreign Service officer John Gunther Dean's bold manuever in enlisting White House deputy chief of staff Michael K. Deaver's help in getting the appointment as U.S. ambassador to India, Foggy Bottom sources say.

Secretary of State George P. Shultz had planned to send another career diplomat, James W. Spain, to head the embassy in New Delhi before Deaver got into the act.

Career officials are even more upset about political intervention to advance the cause of one of their own than they are about politicking on behalf of outsiders.

In a bit of musical chairs, Spain probably will be sent to Indonesia in a few months to replace John Herbert Holdridge as U.S. ambassador. William A. Brown, currently deputy assistant secretary for East Asian and Pacific affairs, is likely to replace Dean as ambassador to Thailand.

In a shuffle involving noncareer officials, J. William Middendorf II will leave his post as ambassador to the Organization of American States on the sixth floor of the State Department for new quarters in Brussels, where he is to become ambassador to the European Economic Community. Moving into the OAS post will be Richard T. McCormack, who has been assistant secretary for economic and business affairs. The new chief of the economic bureau will be John M. Hennessy, a banker who once was an aide to Shultz at the Office of Management and Budget.

No decision has been made about replacements for three other senior Foggy Bottom officials who are expected to leave within a few months: Elliott Abrams, assistant secretary for human rights; Gregory J. Newell, assistant secretary for international organizations, and legal adviser Davis R. Robinson.

In the recently refurbished executive suite on the department's seventh floor, Charles Hill has taken over as Shultz's executive assistant, a job that has been vacant since Raymond G.H. Seitz was assigned to London. Nicholas Platt, formerly ambassador to Zambia, has replaced Hill as head of the executive secretariat.

Edward Djerejian, a former deputy chief of mission in Jordan and political counselor in Moscow, is replacing Alan Romberg as deputy spokesman for the department. Romberg is leaving for the private sector.

In a related area, the new chairman of the Senate Foreign Relations Committee, Sen. Richard G. Lugar (R-Ind.), has named three top committee staff members.

They are Jeffrey T. Bergner, who has been Lugar's foreign policy and legislative aide for six years, who will be committee staff director; M. Graeme Bannerman, a veteran committee staff member, who will be deputy staff director; and Mark Blitz, who was director of private-sector programs for the U.S. Information Agency, to head committee staff operations dealing with the budgets of foreign policy agencies.

Lugar and the committee are planning a series of hearings on American diplomacy with Shultz and Defense Secretary Caspar W. Weinberger, beginning Jan. 31 and lasting for several weeks.