Louis Bonesio, 51, is the first person to live with transplanted organs from two donors.
Eleven years ago, the Gilroy, Calif., man received a heart transplant at Stanford University. A month ago he received a kidney transplant at the University of California, San Francisco. Along the way, Bonesio, who operates a barbecue-catering business, also acquired two artificial hip joints because his own were damaged by drugs he must take to prevent his immune system from rejecting the heart.
Although kidney damage is a common side effect of immunosuppressive drugs, Bonesio's failed because of an unrelated, rare kidney disease.
Bonesio's survival with a transplanted heart ranks among the longest but is well short of the record holder, Emmanuel Vitria, who received a heart transplant in Marseilles, France, nearly 17 years ago.
Stanford, the major heart-transplant center in the United States, reports that 85 percent survive at least one year and 70 percent live more than three years. Survival odds after kidney transplantation are somewhat better.
Bonesio, who went home from the hospital last month, said he would resume a life of "constructive leisure," which includes hot air ballooning, motorcycling, fishing and backpacking.
Bonesio's kidney donor was a man in his 20s who died in a car accident. His heart and lungs were transplanted as a unit at Stanford into a 32-year-old Iowa man. His other kidney went to a 56-year-old man. Both his corneas also were transplanted.