Doctors yesterday transplanted a human heart into a man who lived 11 days with the Penn State artificial heart, hours after surgeons in Pittsburgh performed the same operation for a man kept alive for four days by a Jarvik-7 pump.
Anthony Mandia, 44, first recipient of the Penn State heart, was taken off a heart-lung machine and began relying on a female donor's heart less than three hours after surgery began. Earlier, doctors rejected using another donor heart for him.
That heart, considered too big for Mandia, instead went to Thomas J. Gaidosh, 47, a factory worker who had the Jarvik-7 heart in Pittsburgh. He was reported in critical condition after the 3 1/2-hour procedure, which surgeons described as "routine," a hospital spokesman said.
"The new heart took over . . . very nicely," said Dr. Bartley Griffith, who led the surgical team. "Early indications are that survival is well within his grasp."
Because of degeneration of the heart muscle, doctors had expected Gaidosh to live less than a day when the Jarvik-7 was implanted.
In San Francisco, meanwhile, Richard E. Dallara resumed eating solid food and joked with his family as twin mechanical pumps circulated blood through his body. The Thoratec pumps do not require removal of his natural heart.