The Senate, in a step one Republican said was designed to force the Reagan administration to deal with "what's going on" at the Consumer Product Safety Commission, moved yesterday to strip the commission's chairman of some of his political appointees.

Sen. Alfonse M. D'Amato (R-N.Y.) made no secret that his floor amendment, which would strip $250,000 in political salaries from CPSC's budget, was aimed at the agency's controversial chairman, Terrence M. Scanlon. The amendment to a Department of Housing and Urban Development appropriations bill was approved unanimously. D'Amato predicts that the House will concur.

D'Amato is highly critical of Scanlon's management style, accusing the Reagan administration appointee and his top staff of attempting to destroy the 14-year-old consumer agency. The amendment, D'Amato said, would force Scanlon to discharge about five top aides.

"Some of us in Congress know what's going on over there. It's a travesty," D'Amato said, citing what he calls the agency's inability to enforce safety regulations and issue new ones. "Hell, if that's the way he's going to run the place, this is the way we feel," D'Amato said.

His amendment would take $250,000 from the commission and earmark it for a veterans' cemetery in upstate New York, an action that the senator said would benefit consumers and veterans.

"In taking the money, we've struck a blow for the consumers because he {Scanlon} just used the staff to obstruct the consumers," he said.

An spokesman at the agency said the chairman would have no immediate comment on the amendment.

D'Amato said Scanlon, an strong advocate of seeking voluntary industry action to resolve safety issues, is transfixed by "some crazy ideology that says we never interfere with the marketplace." That attitude will "destroy the enforcement effort, deliberately," D'Amato said, adding, "and I'm a conservative."