Lisa Abood of Kenwood and Kim Williams of Bethesda Country Club, two young women more familiar with a basketball than a golf ball, led the way in the 49th annual Keefer Cup handicap tournament at Chevy Chase yesterday with net 73s.

A stroke behind in the two-day event, which concludes today, were Linda Guglielmi of Congressional and Peg Widicus of Army Navy.

Abood, a substitute teacher who graduated from the University of Maryland last year and now coaches basketball and softball in the Montgomery County high school system, was a varsity basketball player at Maryland. Williams, 18, a senior at Wootton High School in Rockville, also is a varsity basketball player. She has been playing golf only two years, but was good enough this year to play on the boys team.

A group of 67 women teed off in the misty rain, with 33 making the cut at 79. Lois Holzapple, the defending champion, qualified with a net 78.

Only Abood, who turned in a gross 77, was able to break 80 yesterday. She was out in 37 and home in 40 with eight pars and two birdies. She birdied the third hole with a 20-foot putt and birdied the par-5 eighth with a 30-footer. She missed only one fairway all day.

Williams had a 43 going out and came back in 39 for a gross 82. She carries a nine handicap to Abood's four.