Southern California replaced Notre Dame at the top of the Associated Press and the United Press International college football polls yesterday, setting up a big game with No. 2 Oklahoma Saturday in Los Angeles.

Michigan, the preseason leader, was bumped from the top after losing to Washington Sept. 12. But the Wolverines bounced the Irish out of the top 10 by trouncing them Saturday.

That opened the way for USC and Oklahoma, last week's Nos. 2 and 3, to move up. USC, a 21-0 winner over Indiana, received 46 of 65 first-place votes from a panel of sportswriters and sportscasters in the AP poll, and UPI's board of coaches gave the Trojans 28 of 40 first-place votes.

Oklahoma was idle last weekend.

Third, fourth and fifth in both polls were Penn State, Texas and Pittsburgh, respectively. UCLA and Michigan were sixth and seventh in UP, in the reverse order in UPI. Ohio State, North Carolina and Alabama were eighth, ninth and 10th in both polls.

Georgia's defending national champions, 13-3 victims of Clemson, fell from fourth to 17th place, while Clemson made the top 20.

Penn State, idle last weekend, rose from fifth to third with two first-place votes and 1,092 points, while Texas, a 23-10 victor over North Texas State, jumped from sixth to fourth with one first-place vote and 1,038 points.

Pitt went from seventh to fifth with 976 points following a 37-7 rout of Cincinnati and UCLA vaulted from ninth to sixth with 912 points after trimming Wisconsin, 31-13.