Ron Jaworski led Philadelphia to three fourth-quarter touchdowns -- the last a three-yard run by Leroy Harris with 22 seconds to go -- as the Eagles beat the Cleveland Breown, 24-21.
Philadelphia (1-1) had not beaten the Browns since 1967, and had not won in Cleveland since 1960.
The Browns (1-1) had taken a 21-17 lead when tight end Ozzie Newsome, who had a career-high eight catches for 122 yards, wrestled away a 34-yard touchdown pass from defender Roynell Young with 57 seconds remaining.
Jaworksi, who completed 25 of 41 passes for 334 yards in his second straight week over the 300-yard passing mark, threw scoring passes of 41 yards to Ron Smith and 11 yards to Billy Campfield to bring Philadelphia back from a 14-3 deficit.
"There were no breakdowns, nothing critical about our defense on that final drive," said Browns Coach Sam Rutigliano. "It was just perfect execution by them."
Cleveland took the opening kickoff and drove 71 yards, scoring on Brian Sipe's 19-yard pass to Newsome. The drive was aided by an Eagle offsides penalty on a fourth-and-two play on the Philadelphia 27.
The Eagles' ensuing possession lasted more than nine minutes, but Jaworski was stopped at the goal line by Cleveland cornerback Hanford Dixon on a fourth-down play from the two. On Philadelphia's next series, early in the second quarter, Tony Franklin kicked a 47-yard field goal.
The clubs traded punts in the third period, and a poor punt by Eagle Max Runager set up a touchdown by Charles White early in the fourth.