Bobby Clampett, 22, shot a six-under-par 64 yesterday in Columbus, Ga., to win the Southern Open golf tournament by two strokes over Hale Irwin for his first victory in slightly more than two years on the PGA tour.

Clampett, clad in gray knickers and white shoes, won $45,000 for his four-round 266 total.

Irwin shot a tournament record 61 on the par-70 Green Island Country Club course for a 72-hole total of 268.

George Burns, the third-round leader, shot 68 and finished third at 269 . . .

Gene Littler fired his fourth consecutive sub-par round, a two-under-par 70, and finished with an eight-under par 280 to win the $150,000 World Seniors Invitational golf tournament in Charlotte, N.C. . . .

In London, Gordon Brand Jr. became the first professional to win two tournaments in his rookie year on the European tour with his victory in the Bob Hope British Golf Classic. Brand finished with a 69 for a 16-under four-round total of 272, three shots ahead of Mark James . . .

In Kent, Wash., Patty Sheehan parred the final hole for a one-stroke victory in the Ladies Professional Golf Association's $175,000 Safeco Classic.

Sheehan and JoAnne Carner were tied at 12 under par going to the last hole at the Meridian Valley Country Club. Sheehan won $26,250 in the 72-hole tournament.

Auto Racing: Indy-car rookie Bobby Rahal pulled away from Mario Andretti to win the 150-mile Detroit News Grand Prix at Michigan International Speedway in Brooklyn.

Earlier in the race, A.J. Foyt was knocked out of competition when he and Kevin Cogan crashed in the eighth lap; Foyt was treated and released at a hospital in Jackson, Mich., where Dr. Steve Olvey said he had a bruised right leg. Foyt's right wrist was also twisted. Cogan was unhurt . . .

Danny Sullivan, driving for film star Paul Newman's racing team, won his first Can-Am race of the season in Las Vegas after an exciting duel with Al Unser Jr. Sullivan, 31, who had won his first Can-Am race on this same twisting, 2.26-mile track last year, was hugged and slapped by a happy Newman at the end of the race.

Colleges: The University of Mississippi athletic equipment manager and two football team student managers were among 12 people arrested on ticket scalping charges Saturday in Little Rock, Ark., where Ole Miss played Arkansas.

W. Blake Barnes, the equipment manager, was charged with selling 15 $13 tickets to the sold-out game at $30 each, police said. Barnes paid a $77 fine and was released, police said.

Cycling: Bernard Hinault, winner of this year's Tour de France and Tour d'Italy, won the Grand Prix des Nations in Cannes. Daniek Gisiger was second, two minutes back.

Horse Racing: Christ-mas Past, ridden by Jacinto Vasquez, won her third important stakes in four starts when she drew out in the stretch and won the $166,800 Ruffian Handicap for fillies and mares at Belmont Park. The 3-year-old filly carried 117 pounds over the 1 1/8 miles in 1:48 3/5 in beating Mademoiselle Forli by five lengths.

Moose Hunting: In Greenville, Maine, state game officials said preliminary reports indicate 880 moose were bagged during the six days of Maine's second moose season since 1935. One thousand hunters, chosen by lottery, were allowed to take part in the hunt with a limit of one moose each. The season ended at sundown Saturday.