Defenseman Ray Bourque, playing in his fifth game since an injury, scored two goals and assisted on two others as Boston beat visiting St. Louis.
Peter McNab broke a 1-1 tie in the second period and Brad Palmer scored just 65 seconds later to give the Bruins a 3-1 lead.
Bourque, who suffered a fractured facial bone late in the exhibition season, scored his first goal while the teams were skating four a side at 1:54 of the middle period.
St. Louis tied the score, 1-1, on a goal by Vaclav Nedomansky on a power play less than three minutes later. Nedomansky's 55-foot shot snapped Boston's string of killing 22 penalties in a row since Oct. 27.
McNab broke the deadlock at 7:55 from close up, and Palmer followed with his goal at 9:00. Barry Pederson made it 4-1 late in the second period with Boston's second short-handed goal of the season.
Luc Dufour tallied for Boston early in the third period before the Blues got a goal from Perry Turnbull and a short-handed goal from Wayne Babych.
Keith Crowder tipped in a shot by Bourque on a Boston power play before Bourque completed the scoring on a long slap shot.