In Monroe, La., freshman Chana Perry had 31 points and 14 rebounds to power No. 2 Northeast Louisiana past fourth-ranked Louisiana Tech, 85-76, in the Midwest Regional.
Northeast moves into the first round of the Final Four against No. 5 Old Dominion, which won the East Regional Saturday night.
Northeast's 21st consecutive victory at home gives it a 30-1 record -- best in the nation -- and a 15-game winning streak. Tech finished at 29-4.
Northeast Louisiana let Tech lead just once -- at 35-34 a moment before halftime -- after the score was tied five times in the first half. And Northeast hit 10 of its first 12 field goals of the second half to take control.
The Indians used a 3-1 zone with a Chrissa Hailey as floating guard to limit Tech all-America Pam Gant, who entered the game with a 24-point average, to 14 points.
Tech assist leader Teresa Weatherspoon, out with a thigh injury, was replaced by freshman Tatia Brown, who scored a career-high 17 points.
Tech was led by Tori Harrison's 29 points.
For Northeast, Lisa Ingram had 23 points and 12 rebounds and Eun Jung Lee finished with 18 points and 11 assists.