Forward Billy Thompson scored 21 points as 16th-ranked Louisville routed 15th-ranked Virginia Tech, 103-68, in a Metro Conference game last night in Louisville.

It was the first time the Cardinals (15-6, 4-2 in the Metro) have scored more than 100 points since the fifth game of the 1983-84 season. It was Lousville's fourth straight victory. Virginia Tech fell to 18-5, 4-3.

Forward Herbert Crook scored 19 points, guard Jeff Hall had 14 and guard Milt Wagner had 12 for Louisville.

Louisville broke open a close game in the first half with a 14-1 run that was sparked by center Pervis Ellison's slam dunk at 9:35 and ended on forward Tony Kimbro's driving layup at 5:17 for a 36-24 advantage.

After Virginia Tech forward Bobby Beecher hit a 10-footer at 4:39, Louisville outscored the Hokies by 11-4 the remainder of the half to take a 47-30 lead.

Louisville made 21 of 35 shots in the first half for 60 percent; Virginia Tech hit 12 of 33 for 36 percent.

Dell Curry and Keith Colbert had 14 points each for Virginia Tech. Michigan 80, Purdue 79

Roy Tarpley scored 18 points as the seventh-ranked Wolverines capitalized on a five-minute scoring drought by Purdue to hold onto first place in the Big Ten with the road victory.

Michigan moved to 20-2, 8-2 in the conference. Purdue fell to 16-7, 5-5 with its fourth straight league loss.

Michigan was leading by 59-54 when the Boilermakers took their only lead of the second half with a seven-point streak. Todd Mitchell (21 points) made two free throws to give Purdue a 61-59 lead with 10:34 left, but the Boilermakers then failed to score until a Mitchell basket with 5:10 left.

Garde Thompson tied it at 61 and Gary Grant's three-point play broke the tie with 8:37 left.

The Wolverines opened a 75-67 lead with 2:31 left on Butch Wade's jump shot. Purdue responded with six straight points on Mitchell's basket and Troy Lewis' two baskets to close to 75-73.

Purdue pulled to 76-75 with 34 seconds left on Mack Gadis's basket. Antoine Joubert made two foul shots for Michigan with 30 seconds to go and Richard Rellford's two free throws with 17 seconds remaining put the Wolverines up by 80-75. Indiana 78, Wisconsin 69

Steve Alford had 16 of his 23 points in the second half to lead the 18th-ranked Hoosiers (15-5, 7-3) to the Big Ten victory at home. Indiana has beaten Wisconsin (10-10, 2-8) nine straight times at Assembly Hall.

Alford's 20-foot jumper put the Hoosiers ahead to stay at 50-48 with 12:18 left. With Indiana ahead, 54-52, the Hoosiers went on a 6-0 run with baskets by Courtney Witte, Stew Robinson and Winston Morgan.

"I was really pleased with Witte's play," said Indiana Coach Bob Knight. "We really needed someone to come in and do things inside. He made some good defensive plays and got his hands on the ball." Georgia Tech 87, N.C.-Charlotte 76

In Atlanta, freshman Tom Hammonds made 10 of 12 shots for a season-high 24 points as the second-ranked Yellow Jackets (18-3) overcame a sluggish first half.

N.C.-Charlotte (5-15) held a 42-37 lead before Georgia Tech opened the second half with a 9-0 run. It was the 49ers' ninth straight loss.

Georgia Tech's Mark Price had 18 points. Bruce Dalrymple had 14 points, 10 rebounds and 10 assists. Old Dominion 74, Western Kentucky 61

In Norfolk, Va., Kenny Gattison had 22 points and 12 rebounds as the Monarchs upset the 19th-ranked Hilltoppers (18-4, 7-2) in a Sun Belt Conference game.

Old Dominion (15-5, 8-2) took command in the first half. The Monarchs went on an early 8-0 run with Keith Thomas' 20-foot jumper with 14:52 left giving them a 10-2 lead. Old Dominion led at the half, 39-27. Virginia Commonwealth 63, Alabama-Birmingham 57

Forward Michael Brown keyed a second-half surge that erased a seven-point deficit and helped the Rams (10-12, 5-5) win the Sun Belt Conference game at home.

The Blazers (20-7, 8-4) took a 31-24 lead after Anthony Gordon scored the first basket of the second half, but VCU went on a 23-7 run as Brown scored eight points. Brown finished with 19 points and Bruce Allen had 14. Nevada-Las Vegas 93, Pacific 72

Eldridge Hudson scored 12 of his 20 points in the first eight minutes of the second half to help the ninth-ranked Runnin' Rebels (22-2, 11-0) win the Pacific Coast Athletic Association game at home.

UNLV's Anthony Jones scored 18 points and Freddie Banks had 14. Texas-El Paso 72, Wyoming 58

Dave Feitl had 20 points Quintan Gates scored 14 of his 18 points in the first half to help the 17th-ranked Miners, at home, to the Western Athletic Conference victory. It marked the fourth time in five seasons the Miners (20-3, 8-2) have won at least 20 games.