TORONTO, SEPT. 13 -- David Segui and Steve Finley drove in two runs apiece in a five-run sixth inning and Jose Mesa held the Toronto Blue Jays to six hits over 6 2/3 innings tonight for his first victory of the season, as the Baltimore Orioles won at Skydome, 5-3.

It was Toronto's second straight loss after a six-game winning streak. The Blue Jays began play four games behind Boston in the AL East.

"Chalk this one up to a combination of two things," Toronto third baseman Kelly Gruber said. "There's no question we were tired. You're looking at a team that didn't get in until early in the morning. That was one factor. The other was Jose Mesa. He pitched effectively, well enough to win."

Mesa struck out three and walked four before giving way to a parade of relievers.

With the game scoreless, Cal Ripken started the sixth with a double and Sam Horn walked. Mickey Tettleton singled and the throw from right fielder Junior Felix was right on target but catcher Pat Borders caught the ball in front of the plate, giving Ripken room to slide in safely.

Craig Worthington walked to load the bases and Segui doubled to score Horn and Tettleton. Dave Stieb (18-6) struck out Billy Ripken, but Finley delivered a two-run single that knocked out Stieb.

"Maybe Stieb is the type of pitcher {Segui} handles," Baltimore Manager Frank Robinson said. "That's not to say he will always do well against Stieb. He can be tough on most hitters."

The Blue Jays made it 5-2 in the seventh. Rob Ducey drew a leadoff walk and scored on a double by Borders, who later scored on Felix's grounder.

Joe Price relieved after Mookie Wilson's two-out single. He walked Tony Fernandez, bringing Gruber to the plate representing the tying run. Jose Bautista relieved and threw one pitch, retiring Gruber on a pop foul.

George Bell began the Toronto eighth with a single and Jeff Ballard relieved Bautista. Fred McGriff flied out to center and pinch hitter Kenny Williams forced Bell but reached second when second baseman Billy Ripken made a throwing error while trying to complete a double play.

Gregg Olson relieved and yielded a run-scoring single to pinch hitter Rance Mulliniks before recording his 31st save.