Notre Dame pulled off another NCAA tournament upset on another opponent's home court.

La'Tania Severe scored 17 points and 11th-seeded Notre Dame made six straight free throws in the final 1 minute 1 second to beat No. 3 seed Kansas State, 59-53, in an East Region second-round game in Manhattan, Kan.

Notre Dame (21-10) frustrated a team that had been averaging 75 points with an active zone defense and patient offense and advanced to the round of 16 for the fifth time in seven years.

The Irish will play second-seeded Purdue in the regional semifinals Sunday in Dayton, Ohio. The teams met in the 2001 national championship game, won by Notre Dame, which also scored upsets of higher-seeded teams on their home courts in 1997 and '98.

Even with its potent offense, Kansas State (29-5) couldn't recover after going 12:44 without a field goal and had a 22-game home winning streak broken. Notre Dame took advantage of the Wildcats' struggles to open a 45-38 lead on Megan Duffy's three-pointer with 7:45 left, just enough of a cushion to hold on down the stretch.

"I thought for whatever reason that mentally we really froze," Kansas State Coach Deb Patterson said. "We were our own worst enemies a lot of possessions in the second half. I haven't seen this team play like this all year. It snuck up and got us."

Duffy, who had been 5 for 30 from behind the arc coming in, had put Notre Dame ahead to stay at 35-32 with a three-pointer and made four of the late free throws. Her reward will be a trip to her home town for the next round.

Kansas State, cheered on by a purple-clad crowd of 11,534, managed a late run, but Notre Dame kept making free throws every time the Wildcats got within two points.

Nicole Ohlde's layup with 28 seconds remaining left Kansas State trailing 55-53, but Duffy made two free throws to take the lead back to four. Kansas State's last hopes ended when Chelsea Domenico missed a three-point shot and Jacqueline Batteast rebounded for Notre Dame. Severe then made two final free throws.

* CONNECTICUT 81, TEXAS CHRISTIAN 66: Diana Taurasi scored a career-high 35 points to lead the top-seeded Huskies past the ninth-seeded Lady Frogs in Storrs, Conn.

The junior guard had 10 points in an 18-2 run to open the second half, erasing a two-point halftime deficit. U-Conn. (33-1) has trailed three times in the last 87 games, and for most of the first half, the Huskies' home-winning streak of 62 games was in jeopardy.

U-Conn. will play Big East rival Boston College in the East Region semifinal on Sunday in Dayton, Ohio.

Against the ninth-seeded Lady Frogs (20-14), U-Conn. ran into a team just as big and fast. Its problems started in the middle against center Sandora Irvin, who led TCU with 19 points and nine rebounds.

Ashley Battle finished with 16 points and a team-high 11 rebounds for the Huskies.