Adam Eaton pitched seven sharp innings, Phil Nevin hit a three-run homer and the San Diego Padres capitalized on Mike Mussina's early departure to beat the Yankees, 10-2, yesterday in New York.

Mussina left after just three innings because of tightness in his right groin. He came out as a precaution, the Yankees said. His injury occurred two days after teammate Kevin Brown left his start against Colorado with a strained back.

"I'm not concerned about it," Mussina said. "It doesn't hurt walking around, just stretching down from the mound."

Nevin connected in the ninth, and Mark Loretta had two doubles, an RBI and three runs scored for the Padres, who jumped on reliever Felix Heredia (0-1) in the fourth to snap a 1-1 tie. San Diego beat New York in its first game at Yankee Stadium since losing Game 2 of the 1998 World Series.

The Yankees lost their first interleague game since being no-hit by six Houston pitchers exactly a year ago. They had won 13 straight interleague matchups and four in a row overall.

Eaton (3-6) has won consecutive starts after losing six straight decisions. He allowed four hits and two runs while striking out four and walking three. He gave up two runs in six innings against Milwaukee on Sunday.

The Yankees played Ray Charles' rendition of "America the Beautiful" during the seventh inning stretch in honor of the singer, who died Thursday.

* RED SOX 2, DODGERS 1: David Ortiz singled in the winning run in the bottom of the ninth after homering in the seventh in Los Angeles' first game ever at Fenway Park.

After left fielder Manny Ramirez's error gave the Dodgers an unearned run in the top of the ninth, Johnny Damon started the bottom of the inning by walking against Tom Martin (0-1).

Damon went to third on Mark Bellhorn's double to left, and scored on Ortiz's single just inside the right field line.

Keith Foulke (2-0) got the win after Derek Lowe pitched seven scoreless innings and Mike Timlin also threw a shutout inning.

The Red Sox seemed to have the game wrapped up when Olmedo Saenz hit a windblown popup to medium left in the ninth off Foulke. There were two outs and Alex Cora, who had singled, was on first. Ramirez ran in and tried to make a basket catch, but the ball dropped just to his left for an error as Cora kept running and scored.

"I just went hard. I gave it my best and I dropped the ball," Ramirez said, before joking: "There goes my Gold Glove."

* TIGERS 8, MARLINS 4: Ivan Rodriguez homered in his first game against his former team, helping host Detroit beat Florida.

Dmitri Young hit a three-run shot for his first homer of the year, and Carlos Guillen added a two-run drive for the Tigers.

Rodriguez, the star catcher who helped Florida to a surprising World Series title last October, went 2 for 4 with a single.

"Mr. Rodriguez is a special player, and we could spend an hour saying good things about him," Tigers Manager Alan Trammell said.

* ROYALS 7, METS 5: Matt Stairs doubled and tripled to help Darrell May avoid becoming the majors' first nine-game loser, and host Kansas City beat slumping New York.

In their first appearance in Kauffman Stadium, the Mets lost their fourth in a row and their sixth in seven games.

* BREWERS 9, ASTROS 3: Scott Podsednik hit a three-run homer and an RBI double to back a solid outing by Doug Davis in host Milwaukee's victory.

Geoff Jenkins and Junior Spivey also homered for the Brewers, who have beaten Tim Redding three times this season.

Jeff Kent extended his career-best hitting streak to 25 games -- a franchise record and the longest in the majors this season -- with a leadoff double in the second. He broke the mark he shared with Tony Eusebio, who hit in 24 straight in 2000.

* DEVIL RAYS 8, ROCKIES 7: Rey Sanchez hit an inside-the-park homer in the 10th to lead host Tampa Bay to victory. Sanchez hit a liner to right field off Shawn Chacon (0-3) that went all the way to the wall after Jeromy Burnitz missed a shoestring catch attempt. Center fielder Choo Freeman backed up the play and retrieved the ball, but Sanchez was already headed home with the winning run.

* BRAVES 6, WHITE SOX 4: Jaret Wright pitched two-hit ball for seven scoreless innings and Eli Marrero hit a three-run double in Atlanta's win in Chicago. The White Sox rallied for four runs against John Smoltz in the ninth on Carlos Lee's RBI double and Jose Valentin's three-run homer. But Smoltz struck out pinch hitter Timo Perez with a runner on to end it.

* DIAMONDBACKS 3, BLUE JAYS 2: Danny Bautista hit a go-ahead single in the ninth and visiting Arizona rallied to victory.

Actress Kim Cattrall from HBO's "Sex and the City" threw out the ceremonial first pitch.

* INDIANS 6, REDS 5: Pinch hitter Lou Merloni drew a bases-loaded walk in the 11th, and Cleveland rallied to win at home.

Coco Crisp went 4 for 4 for the Indians, who improved to 4-7 in extra innings.

* CARDINALS 12, RANGERS 7: Albert Pujols returned from a hamstring injury and drove in a run, and John Mabry homered and had five RBI. Reggie Sanders homered had three hits for the Cardinals, who have a major league-best 22-11 record on the road.

* PHILLIES 11, TWINS 6: Ricky Ledee's three-run homer, his second of the night, capped a five-run ninth that ended host Minnesota's four-game winning streak.

* ATHLETICS 6, PIRATES 1: Tim Hudson allowed one run in seven innings to lead host Oakland to its season-high sixth straight win.

Damian Miller and Marco Scutaro each drove in two runs for the A's, who sent the Pirates to their sixth consecutive defeat.

* MARINERS 1, EXPOS 0: Seattle ended a 29-inning scoreless drought when Pat Borders's bases-loaded single with two outs in the ninth gave the Mariners a victory at home.

The Mariners hadn't scored since Scott Spiezio homered in the fifth inning of a 5-0 win over Houston on Monday night. The Astros shut out Seattle 3-0 on Tuesday night and 1-0 Wednesday night.

* ANGELS 3, CUBS 2: John Lackey outpitched Greg Maddux, and host Anaheim beat Chicago.

Lackey (4-7) held the Cubs to two runs and seven hits in seven innings. He struck out six, walked one and won for the first time in five decisions.

With closer Troy Percival on the disabled list, Francisco Rodriguez pitched a perfect ninth for his fourth save and second in two nights.

Maddux (5-5) gave up three runs and seven hits in seven innings, with six strikeouts and no walks.