Pittsburgh (+4) at Baltimore, 1 p.m. (WUSA-9, WJZ-13)
Jerome Bettis's one-yard, three-touchdown performance got all sorts of attention last week, but Duce Staley remains the Steelers' number one running back. Pittsburgh's defense only gave up 201 passing yards last week if you take away the two big touchdown passes it surrendered.
Houston (+3) at Detroit, 1 p.m.
The Lions were impressed with rookie wide receiver Roy Williams's toughness last week against the Bears. He led the team with four catches and also didn't back down from defensive backs who tried to bump-and-run him. "He threw the DB down one time, just threw him down and released," Detroit Coach Steve Mariucci said.
St. Louis (+2) at Atlanta, 1 p.m.
The Rams have notched seven straight wins over the Falcons and have scored 30 or more points in each of those victories. The Rams' rushing attack could be powerful if Marshall Faulk stays healthy: Faulk had 128 rushing yards last week, while Steven Jackson had 50.
Chicago (+81/2) at Green Bay, 1 p.m.
Bears wide receiver David Terrell didn't quite endear himself to the Chicago coaching staff after last week's game against the Lions. Although he had five catches for a team-high 126 yards, he also gave the crowd (at home, strangely) a double-middle-finger salute.
Denver (-3) at Jacksonville, 1 p.m.
Some in Denver were worried that running back Quentin Griffin was giving away play calls to the Chiefs last week because he seemed to keep his mouthpiece in for running plays and out for passing plays. But it may just be forgetfulness, as Griffin went sans mouthpiece on touchdown runs of 25 and 47 yards.
Carolina (+6) at Kansas City 1 p.m.
Rookie wide receiver Keary Colbert will likely start for the Panthers in place of the injured Steve Smith (broken leg). In his first college start as a Southern California freshman in 2000, he had six catches for 113 yards.
San Francisco (+7) at New Orleans,
Quarterback Ken Dorsey, who will get his first career start for the 49ers, completed 9 of 15 passes for 111 yards last week in relief of the injured Tim Rattay. Expect lots of blitzes from the Saints as they try to rattle Dorsey into making bad plays.
Indianapolis (+11/2) at Tennessee,
Colts defensive end Dwight Freeney has feasted on Titans quarterback Steve McNair over the years. Four of his 25 career sacks have been on McNair. Last week, Freeney had one sack and five pressures against Patriots quarterback Tom Brady.
Seattle (-3) at Tampa Bay, 4:05 p.m. (WBFF-45)
Seahawks running back Shaun Alexander had 135 rushing yards, two rushing touchdowns and a receiving touchdown last week, but he's questionable after suffering a bone bruise on his right knee. Maurice Morris will probably start.
Cleveland (+4) at Dallas, 4:15 p.m. (WUSA-9, WJZ-13)
Cowboys guard Andre Gurode and center Tyson Walter are both questionable with knee injuries, more bad news for a Dallas rushing attack that could only muster 71 yards last week.
N.Y. Jets (-3) at San Diego, 4:15 p.m.
Before last season, Chargers tight end Antonio Gates, who had eight catches for 123 yards last week, had not played football since high school. He was a basketball player at Kent State, helping lead the Flashes to the Elite Eight in 2002.
Buffalo (+31/2) at Oakland, 4:15 p.m.
Oakland's Robert Gallery, the No. 2 pick in this year's draft, will get his first start at right tackle. The Bills have not scored an offensive touchdown in six of their last nine road games.
New England (-8) at Arizona, 4:15 p.m.
New England is gunning for its 17th straight win including the playoffs; the league record is 18. Cardinals Coach Dennis Green has won seven of 10 home openers in his career.
Miami (+41/2) at Cincinnati, 8 p.m. (ESPN)
The Dolphins have won nine straight against the Bengals, last losing to them in 1977. Miami is 18-5 all-time on Sunday night and 31-9 in September since 1992.
Minnesota (+3) at Philadelphia,
9 p.m. Monday (WJLA-7, WMAR-2)
Overshadowed by McNabb, Owens, Culpepper and Moss are running backs Brian Westbrook (119 rushing yards last week) for the Eagles and Onterrio Smith (76 rushing yards and a 63-yard touchdown catch) for the Vikings.