Green Bay (+3) at Detroit, 1
Through the first nine games of last season, Packers running back Ahman Green fumbled seven times. But he didn't fumble over his final 246 touches of the season. Through five games this season, however, Green has fumbled four times, and his output is dropping. He rushed for 119 yards and three scores in the opener, but is averaging just 71.5 yards per game without a touchdown since then.
Miami (+6) at Buffalo, 1
To try to cut down on penalties, the Bills now have two former Arena League officials watching their practices. But penalties are only part of the problem. Buffalo is only scoring 12.8 points per game, the second-worst mark in the league. Luckily, the Dolphins are only averaging 8.4 points, worst in the league.
Houston (+61/2) at Tennessee, 1
The Texans will need to shore up their run defense if they want to beat the Titans for the first time ever. Last week, Vikings rookie Mewelde Moore rushed for 92 yards in his first start. Now comes Tennessee's Chris Brown, who is second in the NFL with 556 rushing yards.
San Diego (+5) at Atlanta, 1 (WUSA-9)
What on Earth is going on here? Chargers quarterback Drew Brees, who San Diego basically left for dead after drafting Philip Rivers, has five touchdowns and zero interceptions over his past two games. Meantime, the West Coast Falcons lead the league in rushing at 158 yards per game.
San Francisco (+10) at New York Jets, 1
The Jets have never started a season 5-0, but their chances are good against the 49ers, who suffered yet another injury last week when linebacker Julian Peterson (Crossland), their best defensive player, tore his Achilles' tendon.
Seattle (+4) at New England, 1
It's a return of sorts for Seahawks quarterback Matt Hasselbeck, who grew up in Massachusetts and played at Boston College. Plus, Hasselbeck's father was a tight end for the Patriots from 1977 to 1983.
Kansas City (-2) at Jacksonville, 1
Eddie Kennison, who has the only 100-yard receiving game for the Chiefs this season, should be back after missing 21/2 games with a hurt hamstring. The Jaguars gave up 176 rushing yards, their most in nearly two years, to the Chargers last week.
Cincinnati (+3) at Cleveland, 1 (WJZ-13)
Cleveland hasn't started 3-0 at home since 1973. Two of quarterback Jeff Garcia's career-best games have come against the Bengals. He threw for a career-high 437 yards against them in 1997 and 344 yards last season, both with the 49ers.
Carolina (+9) at Philadelphia, 1
The Panthers are hurting on defense. Carolina placed Kris Jenkins (Maryland), one of the league's top defensive tackles, on injured reserve this week because of a bum shoulder. Brentson Buckner, Carolina's other starting tackle, missed last week's game against Denver with a knee injury and is questionable today.
Pittsburgh (+3) at Dallas, 4:15 (WUSA-9, WJZ-13)
Think Cowboys Coach Bill Parcells likes rookie Steelers quarterback Ben Roethlisberger? "He's the best prospect I've seen in 10 or 15 years," Parcells said Wednesday. "I haven't seen anybody come into the league like that. The only guy in my coaching [career] that I can say came in the first year and started playing like he is playing is Dan Marino."
Denver (-11/2) at Oakland, 4:15
Denver Coach Mike Shanahan has said he won't reveal his starting running back until game time. Reuben Droughns started at tailback in place of the injured Quentin Griffin and roughed up the Panthers last week for 193 yards. But Griffin is expected to play.
Minnesota (-31/2) at New Orleans, 8:30 (ESPN)
Vikings wide receiver Randy Moss has caught a touchdown pass in nine straight games; with one tonight, he'll become the fifth player in NFL history to catch one in 10 straight. Saints running back Deuce McAllister returned from an injury and rushed for 102 yards last week, but one of his two fumbles last week was returned for a touchdown. New Orleans ended up losing by three.
Tampa Bay (+61/2) at St. Louis, 9 p.m. Monday (WJLA-7, WMAR-2)
It's the fourth time in five years that the Bucs and Rams have played on "Monday Night Football," with Tampa Bay winning the three previous meetings. Brian Griese, who was effective last week when he replaced the injured Chris Simms at quarterback for the Bucs, will start tomorrow night.