Chargers 45, Giants 23

-- Eli Manning finally made it to San Diego, and the payback was deafening and lopsided.

San Diegans booed Manning with fervor -- with an occasional rude chant mixed in -- and exhorted LaDainian Tomlinson and the Chargers to a 45-23 win on Sunday night.

Tomlinson ran for 192 yards and three touchdowns and threw for another score to lead the Chargers on a night that left thousands of ear drums ringing, especially Manning's.

Drew Brees threw two touchdowns for the Chargers (1-2). He was 19 of 22 for 191 yards.

Manning finished 24 of 41, throwing for a career-high 352 yards and two touchdowns for the Giants (2-1).

A few days before the 2004 draft, Manning's camp told the Chargers to take someone else with the No. 1 pick, and implied the Mississippi star would sit out if San Diego selected him.

General Manager A.J. Smith picked Manning anyway, then traded him to the Giants for quarterback Philip Rivers -- taken with the fourth pick -- and a handful of picks.

Chargers defenders said all week they were more concerned about getting a win than getting even with Manning.

Yeah, right.

While the fans booed Manning every time he lined up under center, San Diego's defense was more demonstrative than normal.

After Manning had to call a timeout early in the second quarter deep in New York territory, the Chargers exhorted the crowd. When Donnie Edwards sacked Manning on the next play, fellow linebacker Steve Foley jumped all over Edwards in celebration.

Linebacker Ben Leber drew a roughing-the-passer call after Manning threw a touchdown pass to Plaxico Burress to pull to 21-10 late in the second quarter.

Fans brought signs such as "Hey Eli, Nobody Likes You," "Drew's Your Daddy," and "Daddy's Little Girl," a shot at Manning's father, Archie.

In the front row behind the Chargers' bench, fans pummeled a mannequin that was dressed in Manning's No. 10 jersey and a Giants helmet.

Manning quieted the crowd by leading three scoring drives late in the second quarter to pull the Giants to 21-20.

But the Chargers scored on their first three possessions of the second half to put it away.

Early in the third period, Brees pitched to Tomlinson and the running back rolled right and threw a scoring pass to Keenan McCardell, who for the second time in the game was isolated on a linebacker. The veteran wide receiver went over 10,000 yards receiving for his career.

San Diego came back with a clock-eating drive that Brees finished with a 14-yard touchdown pass to tight end Antonio Gates. It was the first score of the year for Gates, who set an NFL record for tight ends with 13 touchdown passes in 2004.

Tomlinson scored on a five-yard run to make it 42-23, and Nate Kaeding added a 44-yard field goal.

Tomlinson scored on runs of one and three yards in the first half as the Chargers scored on their first three possessions to take a 21-3 lead.

Keenan McCardell beats Giants' Antonio Pierce as he pulls in a 26-yard touchdown pass from Chargers running back LaDainian Tomlinson.