Baltimore (+11/2) at Detroit, 1 p.m. (WUSA-9, WJZ-13)
Remember that Giants-Rams game last week? Now imagine the complete opposite. The Ravens rank 26th in total offense, the "first-place" Lions 29th. The Ravens rank 31st in scoring offense, the Lions 29th.
Chicago (+3) at Cleveland, 1 p.m. (WBFF-45)
Cedric who? Chicago's Thomas Jones is making people forget about Cedric Benson, the No. 4 pick in the draft, with 276 rushing yards and four touchdowns over three games. The Bears also are doing a good job protecting rookie quarterback Kyle Orton, who's been sacked five times.
Miami (+3) at Buffalo, 1 p.m.
Bills QB J.P. Losman, whose 55.9 passer rating does not rank among the top 30 in the league, has been benched twice in the last three weeks. Losman or backup Kelly Holcomb might have a better chance to get going today: All six of the touchdowns scored on the Dolphins this season have been through the air.
New England (+21/2) at Atlanta, 1 p.m.
Breathe easy, Falcons fans. Michael Vick has a mild sprain of his right MCL and should start today. The Patriots, meanwhile, are trying to avoid their first two-game losing streak since 2002, when they lost four straight (a skid that coincidentally began in Week 4 with a loss to the Chargers, who beat New England last week).
New Orleans (+3) at Green Bay, 1 p.m.
The winless Packers are hurting both on and off the field. Starters Na'il Diggs, Mike Flanagan, Ahman Green, Chad Clifton and backups Terrence Murphy and Earl Little are all hurt, and all are questionable for today. The Saints didn't miss injured WR Joe Horn last week in their win over the Bills, as Donte Stallworth had eight catches for 129 yards.
Seattle (+21/2) at St. Louis, 1 p.m.
Rams Coach Mike Martz apparently wants to move on from last week's loss to the Giants, which he called an "anomaly." He chose not to show film of the game to his team on Monday, a rarity. Perhaps he couldn't bear to look again at that reverse he called at the Giants 6, which resulted in a fumble.
Tampa Bay (-3) at New York Jets,
1 p.m. (WTTG-5)
Carnell Williams was the league's top story after rushing for 100 yards in his first three games as a pro, but hamstring and arch problems limited him to 13 yards on 11 carries last week.
Tennessee (+3) at Houston, 1 p.m.
The good: The Texans have scored on 75 percent of their possessions in the red zone. The not so good: They've been in the red zone a league-low four times. QB David Carr has been sacked 20 times this season.
Indianapolis (-151/2) at San Francisco, 4 p.m.
The Colts are a perfect example of why the league's total defense rankings should be taken with a grain of salt. Indianapolis has allowed 320 yards per game, ranking 20th in the league, but only two touchdowns, fewest in the league.
Carolina (-3) at Arizona, 4:15 p.m.
Gambling tip of the week (for recreational purposes only, of course): Three of the Panthers' four games have been decided by three points. Cardinals PK Neil Rackers has kicked 16 field goals this season, the most after four games in league history.
Philadelphia (-3) at Dallas, 4:15 p.m.
The Cowboys are looking to provide more running room for RB Julius Jones.
It's not for a lack of trying: Jones has rushed the ball 96 times, third most in the league, but has 335 yards, which ranks eighth. Eagles QB Donovan McNabb is on pace to throw for 5,332 yards, which would break Dan Marino's single-season record of 5,084.
Cincinnati (+3) at Jacksonville,
8:30 p.m. (ESPN)
Only the Raiders have more than the Bengals' 45 penalties this season. They had 14 last week, and WR T.J. Houshmandzadeh has had two scores called back because of flags. Not to be outdone, the Jaguars had 15 penalties last week in their loss to Denver.
Pittsburgh (+3) at San Diego, 9 p.m. tomorrow (WJLA-7, WMAR-2)
RBs Jerome Bettis and Duce Staley are healthy and ready to play, presenting a conundrum for Coach Bill Cowher. Willie Parker has 327 yards rushing yards, and Verron Haynes is needed on third downs, meaning one of the two returnees likely will sit.