Green Bay (+9) at Cincinnati, 1 p.m.
Despite their woeful recent history, the Bengals have gone 17-7 at home against NFC competition since 1993. The Packers have already lost top wideout Javon Walker and tailbacks Ahman Green and Najeh Davenport for the season, and now won't have wide receiver Robert Ferguson for about a month. They limp in at 1-5, but their past four losses have come by a total of nine points.
Chicago (+3) at Detroit, 1 p.m.
First place in the NFC North is on the line and in order to gain it, the Lions will have to play better against the Bears than they did in Week 2, when they lost in Chicago, 38-6. "That was our bad game of the year," Detroit Coach Steve Mariucci said.
Arizona (+9) at Dallas, 1 p.m.
Even with a poor outing last week, Drew Bledsoe has accumulated the third-most passing yards after seven games in Cowboys history with 1,799. Tops on that list? Vinny Testaverde, with 1,844 in 2004.
Oakland (+1) at Tennessee, 1 p.m.
The Raiders' secondary took a big hit by losing defensive backs Charles Woodson and Derrick Gibson for several weeks. The question is whether the Titans can take advantage: Number one wide receiver Drew Bennett is out, replacement Brandon Jones has a sprained knee and quarterback Steve McNair is dealing with a bad back. The Titans may run the ball more with Travis Henry back from a four-game suspension for violating the NFL's substance abuse policy.
Cleveland (+2) at Houston, 1 p.m. (WJZ-13)
How bad are the Browns? Oddsmakers think they are so bad that they've made Cleveland an underdog to a team that has yet to take a lead this season, let alone win a game.
Jacksonville (-31/2) at St. Louis,
The Rams will attempt to ignore the internal upheaval from Coach Mike Martz's public blast at President of Football Operations Jay Zygmunt. Martz, who is recovering from a heart infection that will cause him to miss the rest of the season, told a St. Louis radio station that Zygmunt prevented him from talking by phone to offensive coordinator Steve Fairchild during last week's win over the Saints. "I was very, very angry, to say the least," Martz said.
Minnesota (+71/2) at Carolina, 1 p.m.
Daunte Culpepper has taken a lot of heat for his poor performances, but it is worth noting that the Vikings' per-game rushing average has decreased steadily from 156.7 yards in 2002 to 84.5 this year. Now they face the NFL's third-ranked rush defense, allowing 77.7 yards per game.
Miami (+2) vs. New Orleans in Baton Rouge, La., 4:05 p.m.
Both teams come into this game desperate to end three-game losing skids. It would probably help Miami's cause if Ricky Williams found a way to improve on his 0.6 yards-per-carry average.
Kansas City (+6) at San Diego,
4:05 p.m. (WUSA-9)
The Chiefs' Tony Gonzalez would like nothing more than to show that the torch of being the NFL's premiere tight end hasn't completely passed from him to the Chargers' Antonio Gates. Currently, Gates leads all players at that position with 430 receiving yards, while Gonzalez has 209, with no touchdowns.
Philadelphia (+31/2) at Denver,
4:15 p.m. (WTTG-5, WBFF-45)
The Eagles look to sweep the AFC West this season, which also would be the first time they've beaten all their AFC opponents since 1991. Broncos cornerback Champ Bailey is looking forward to his all-pro matchup against Terrell Owens. "I'm ready for him," Bailey said. "You always look forward to facing guys like him."
Tampa Bay (-11) at San Francisco, 4:15 p.m.
On Oct. 2, Tim Rattay started at quarterback for the 49ers while Brian Griese did likewise for the Buccaneers. The next week, Rattay was benched in favor of No. 1 overall pick Alex Smith. The following week, Griese suffered a severe knee injury, which led to Rattay getting traded to Tampa Bay. This week's turn of events finds Rattay backing up Chris Simms and watching Ken Dorsey start for the 49ers, as Smith sits out with a knee injury.
Buffalo (+9) at New England,
8:30 p.m. (ESPN)
This is the latest point in a season the Patriots have begun divisional play, and given their brutal non-divisional schedule -- those opponents currently hold a combined record of 39-19 -- a stretch of games against the underwhelming AFC East couldn't be more welcome. New England could also get a lift from possibly seeing team leader and Pro Bowl linebacker Tedy Bruschi return to action less than nine months after suffering a stroke.
Baltimore (+10) at Pittsburgh, tomorrow, 9 p.m. (WJLA-7, WMAR-2)
The Ravens face a tall order simply to keep this game competitive, as they now have a depleted defense to go with an offense that has been inept all season. Linebacker Ray Lewis (thigh) will join safety Ed Reed (ankle) on the inactive list; they are the past two NFL defensive players of the year.