Texans07100 -- 17Colts71473 -- 31
Peyton Manning carved up the Houston defense for 297 yards and three touchdowns, leading unbeaten Indianapolis.
Manning completed 26 of 35 passes, and Marvin Harrison had seven catches for 108 yards and one touchdown, making Manning and Harrison the only tandem to top 10,000 career yards. The duo has now hooked up for 755 completions, 10,034 yards and 90 touchdowns -- all NFL records.
Edgerrin James ran 26 times for 122 yards and one touchdown, his 47th career 100-yard game. James is now tied with Franco Harris for the eighth-most in NFL history and topped the 1,000-yard mark for the fifth time.
James and Harrison each had 100 yards in the same game for the 21st time, breaking the previous NFL record of 20 set by Dallas's Emmitt Smith and Michael Irvin.
Colts Coach Tony Dungy had worried all week about the Colts' response to their emotional Monday night victory at New England, and at times, Indianapolis had its problems.
While Indianapolis looked sharp initially, two short punts hit Colts blockers as they ran downfield. The Texans recovered both muffs and converted them into 10 points, keeping Houston closer than expected to the NFL's hottest team.
Indianapolis: Clark 14 pass from Manning (Vanderjagt kick), 4:29.
Indianapolis: James 5 run (Vanderjagt kick), 11:14.
Indianapolis: Stokley 21 pass from Manning (Vanderjagt kick), 5:36.
Houston: Wells 14 run (K.Brown kick), 1:53.
Houston: Gaffney 13 pass from Carr (K.Brown kick), 8:26.
Indianapolis: Harrison 30 pass from Manning (Vanderjagt kick), 5:54.
Houston: FG K.Brown 24, :59.
Indianapolis: FG Vanderjagt 45, 11:30.
TexansColtsFirst Downs 1126Total Net Yards 209419Rushes-Yards 24-8329-126Passing 126293Punt Returns 3-93-7Kickoff Returns 6-1434-82Interceptions Ret. 0-00-0Comp-Att-Int 16-25-026-35-0Sacked-Yards Lost 3-121-4Punts 6-36.83-45.7Fumbles-Lost 2-03-2Penalties-Yards 4-356-50Time Of Possession 27:2532:35RUSHING
Houston: Wells 15-58, Morency 6-18, Carr 2-9, A.Johnson 1-(minus 2).
Indianapolis: James 26-122, Manning 3-4.
Houston: Carr 16-25-0-138.
Indianapolis: Manning 26-35-0-297.
Houston: A.Johnson 4-42, Morency 3-19, Wells 3-17, Gaffney 2-29, Armstrong 2-25, Rivers 2-6.
Indianapolis: Wayne 8-72, Harrison 7-108, Stokley 6-73, James 3-26, Clark 2-18.
MISSED FIELD GOALS