Pennsylvania's Joey Rhoads sank a three-pointer with 4.9 seconds remaining in regulation to force overtime, but American limited the Quakers to just three points in the extra period to hang on for a 70-68 win at Bender Arena.
The Eagles (3-5) scored four straight in overtime and survived poor free throw shooting (10 of 24 total) to claim the team's second overtime win of the season.
American senior guard Tala Hadavi scored a team-high 16 points and juniors Tara Williams and Abby Lipskis each added 13 points.
Rhoads led all scorers with 27 points as the Quakers (1-7) lost their seventh straight game.
* HOWARD 93, MARYLAND-EASTERN SHORE 90: The Lady Bison (2-4) scored seven of the final nine points in overtime to knock off the Lady Hawks (1-4) at Burr Gymnasium.
Sophomore guard Shannon Carlisle scored 23 points to lead four Howard players in double figures. Senior guard Brittany James added 17 points and sophomore guard Christina Aden and freshman guard Loncie Kenley each scored 15.
* VIRGINIA TECH 70, LIBERTY 60: Kerri Gardin scored 20 points and grabbed 14 rebounds as the Hokies improved to 8-0 by knocking off the Flames in Blacksburg.
Megan Finnerty scored 11 points and Dawn Chriss added 10 as Virginia Tech remained perfect against Liberty (3-3) in 12 meetings.
* GEORGE MASON 64, BROWN 59: Moni Akintunde scored 17 points and grabbed 10 rebounds and Jen Daniels tallied a game-high 19 points to help the Patriots rally from a halftime deficit to top the Bears in Providence, R.I.
Brown (3-5) took its largest lead, 45-36, with just more than nine minutes remaining in the second half before George Mason went on an 18-8 run to go ahead for good with 7 minutes 11 seconds remaining.
The Patriots (4-4) limited Brown leading scorer Sarah Hayes to just 11 points, her lowest output of the season.
Patriots junior Nikkia Slade contributed 15 points and seven rebounds.
* GEORGE WASHINGTON 77, STONY BROOK 55: The Colonials (3-3) sailed past the Seawolves (4-3) from start to finish at Smith Center.
The Colonials raced out to an early 9-0 lead and led 39-17 at the half.
George Washington shot 45 percent from the floor en route to its highest points total of the season. Senior forward Jessica Simmonds led the Colonials with 14 points and 13 rebounds and junior guard Kenan Cole added 11 points.
Sophomore guard Kimberly Beck had 10 points.