(Courtesy Virginia State Police.)

State police spokeswoman Corinne Geller says the commercial tour bus ran off the road and turned onto its roof about a quarter mile south of the Carmel Church exit. The accident was reported to state police at 4:55 a.m. Tuesday.

Geller says police haven’t determined how many people were on the bus, which can hold 59 passengers. The injured were taken to hospitals in Richmond and Fredericksburg.

The bus’ destination hasn’t been released. The cause of the crash hasn’t been determined.

The Virginia Department of Transportation says the northbound lanes are expected to remain closed at mile marker 104 for several hours.