Two people were killed and three others injured in a multi-vehicle crash in the Largo area Monday afternoon, fire officials said.

Mark Brady, a Prince George's County Fire/EMS spokesman, posted on Twitter that two people were killed, one man was seriously injured but is expected to survived, and two others sustained minor injuries in a crash in the 13600 block of Central Avenue.

State police would not confirm details of the injuries but said the crash had shut down Central Avenue in both directions between Church and Enterprise roads.