The annual Susan G. Komen Race for the Cure is scheduled for Saturday morning. The fund-raising event for breast cancer research is likely to draw 40,000 runners and walkers to the starting lines along Madison Drive on the National Mall.

Many of the participants and spectators will get to Mall via Metrorail, which will open at 5 a.m. Saturday, two hours earlier than normal, to accommodate them.

The runners will start at 8 a.m. at Seventh Street and Madison Drive, then the walkers will get going at 8:15 a.m. just to the east at Fourth Street and Madison Drive

Both routes go west on Constitution and Virginia avenues, then return the same way to 15th Street NW by the Washington Monument and along Jefferson Drive to the finish line on Independence Avenue. See a pdf map of the route.

There will be temporary street closings along the 3.1 mile route until all of the participants have cleared the area, which should be about 11 a.m.

The closest Metro stations are Smithsonian and Federal Center SW on the Blue and Orange lines, Archives on the Green and Yellow lines, L’Enfant Plaza on the Blue, Orange, Green and Yellow lines and Judiciary Square on the Red Line.

The most crowded stations are likely to be Smithsonian, Federal Center SW and Archives. It’s a good idea to load up your paper Farecard or plastic SmarTrip card to cover a roundtrip and avoid waiting in long lines at the fare vending machines after the event.

Parking at Metro lots and garages is free on weekends, but note Metro’s plans for weekend maintenance work, which will cause delays on some segments of the Blue and Red lines. Add about 30 minutes to travel plans if you’re going through those work zones.

Metro weekend maintenance

Blue Line

From 10 p.m., Friday through closing on Sunday, trains will share one track between Stadium-Armory and Addison Road stations.

All day Saturday, Blue Line trains will operate a shortened route, between Huntington and Largo Town Center. Metro will operate a special shuttle train on a single track between Franconia-Springfield and King Street stations.

Throughout the weekend, every other Blue Line train traveling in the direction of Largo Town Center will terminate at Stadium-Armory Station.

Red Line

From 9:30 p.m. Friday through closing on Sunday, trains will share a track between Grosvenor and Twinbrook..From 10 p.m. Friday through closing on Sunday, trains also will share a track between Takoma and Forest Glen.

Throughout the weekend, all Red Line trains will leave about every 24 minutes from the ends of the line at Shady Grove and Glenmont. On Saturday and Sunday between 9 a.m. and 9 p.m., additional trains will operate in the interior portion of the line between Grosvenor and Takoma. In that zone, trains will arrive about every 12 minutes.