The Belgian former No. 1 suffered the injury last month at the Sony Ericsson Open in Florida and her return to fitness has been much slower than expected.
“My current physical condition does not allow me to be ready for Roland Garros,” Clijsters said Tuesday.
Clijsters, 28, said she will focus on her grass court game to prepare for the London Olympics and Wimbledon as she continues her final season on the women’s tour.
A four-time grand slam singles champion, Clijsters returned to tennis after a two year retirement during her pregnancy and immediately rose back to the top of the world rankings. She capped her comeback with the 2011 Australian Open title, and boasts a career record of 513-124.