View Photo Gallery: Peyton Siva helped the Cardinals get past upset-minded Davidson in Portland.

Fresh off a Big East tournament title run, Louisville earned a No. 4 seed and a first-round matchup with 2008 Cinderella Davidson. And after consecutive first-round exits — including a stunning loss to 13th-seeded Morehead State last year — the Cardinals became a popular upset pick.

But Peyton Siva and company snuffed out Davidson’s hopes of another magical March run with a 69-62 win in Portland.

Siva — whose steady hand guided Louiville on its Big East title run — led the way with 17 points and six assists before fouling out while forward Chane Behanan added 14 points and 11 rebounds and Kyle Kuric chipped in 13 points.

The Cardinals move on to face No. 5 New Mexico or No. 12 Long Beach State in Saturday’s third round.

With Stephen Curry leading the way, the Wildcats advanted to the region final in 2008, falling to eventual champions Kansas in a 59-57 nail-biter. But in their first trip back to the Big Dance since, junior forward Jake Cohen shouldered the offensive load with a game-high 24 points, but his supporting cast could not counter Louisville’s balanced production.

The Wildcats tried to play catch-up from behind the arc, but hit just four of 19 three-pointers and shot only 35 percent overall.

Box score: Louisville 69, Davidson 62

More from Washington Post Sports

Murray State races past Colorado State 58-41

Rodney McGruder leads Kansas State past Southern Miss

Scott Drew tries to alter perceptions at Baylor

Fab Melo ruled ineligible for NCAA tournament

March Madness: Interactive bracket & tourney history

Obama picks Tar Heels to win it all

NCAA tournament quiz: Can you locate the schools?

Locals in the 2012 NCAA men’s tournament

2012 NCAA tournament bracket predictions

Feinstein’s regional analysis: East | Midwest | South | West