Terrell Thomas, at the moment at which his anterior cruciate ligament gave way. (Bill Kostroun / AP)

Cornerback Terrell Thomas was lost for the season after tearing his anterior cruciate ligament in a collision with teammate Jason Pierre-Paul as they blitzed Jay Cutler with seconds left in the first half of the game against the Chicago Bears. The gravity of the injury to Thomas, who has led the team with five interceptions the last two seasons, was instantly apparent.

“It’s devastating,” Justin Tuck said in a sideline interview. “He was primed to have another great year for us. We don’t know who is going to have to step up but somebody is going to have to step up to fill that void. That’s a big void.”

“I kind of wanted to cry for him,” said cornerback Prince Amukamara, the Giants’ first-round draft pick who isn’t likely to play until October as he recovers from a broken bone in his foot. “The expectation bar just feels like it just got a lot higher for me.”

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The Giants also lost cornerback Brian Witherspoon, who is believed to have suffered a sprained medial collateral ligament. He will undergo an MRI today. The defense previously lost cornerback Bruce Johnson with a torn Achilles. Defensive end Osi Umenyiora underwent knee surgery last week and is expected to be out until October as well