Brothers, from left, Ezekiel, Rahm and Ari Emanuel in the March issue of Vanity Fair. (Annie Leibovitz)

Get ready — the Emanuel boys are are finally taking their show on the road. They’re the hottest brother act since the Kennedys: tougher than the Mannings, smarter than the Baldwins, more profane than the Sheens.

We speak, of course, of firstborn Ezekiel “Zeke” Emanuel, 55, oncologist, bioethicist and health care adviser to President Obama; middle brother Rahm, 53, former White House chief of staff and mayor of Chicago; and baby Ari, 51, the Hollywood agent so powerful he inspired the character of Ari Gold on “Entourage.”

“The impatient, pushy Emanuel style is so well known that during a recent job interview I was asked, point-blank, whether I had the levelheaded temperament the position required,” writes Zeke in his upcoming “Brothers Emanuel: A Memoir of an American Family.”

Also: Wicked smart, aggressive and media-savvy. The trio will lead the publicity juggernaut for the book, which comes out in late March. First an excerpt in Vanity Fair’s Hollywood issue with a photo spread by Annie Leibovitz, strategic TV appearances and other supersecret interviews. (Which probably explains why they didn’t get back to us for comment Tuesday. )

Ezekiel “Zeke” Emanuel (J. Scott Applewhite/AP)

A Random House spokeswoman couldn’t tell us why Zeke decided to write the memoir or if his brothers — the three are both famously competitive and close — signed off on the book. But we do know a little more about how the three middle-class kids from Chicago, quick to yell or throw a punch, grew up:

• Rahm “always heard from teachers that they expected the same straight-A performance they’d gotten from me,” writes Zeke. “Though fiercely intelligent, especially when it came to sizing people up and assessing a social situation, he was not naturally inclined to sit at a desk and put in extra effort to turn a B into an A.” Their father used to say, “Rahm always tries to get the maximum for the minimum.”

• Ari was adorable, jittery and always an operator: Selling his school lunch dessert, running a lawn-mowing business (friends did the work, he pocketed the profit) and ordering the most expensive items on the menu.

• And Zeke? Something of a jerk when he first arrived at Amherst, he insists: “Not surprisingly, given my family of origin, I began many relationships there with arguments. I considered this perfectly normal. As it turned out, hardly anyone else felt the same way.”

Other family traits? Sarcasm and “eye-rolling snobbery,” he writes. Somehow, it works for them: “No one is more critical of me than my brothers, but no one is more supportive and loyal. The bond we formed together is unbreakable.”

Read more from Vanity Fair’s excerpt: Ari, Ezekiel, and Rahm Emanuel’s Upbringing: Their Tight Bond, Childhood Dustups, and Skirmishes with Racist Bullies

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