“Mike & Molly,” a Chuck Lorre comedy. (RICHARD CARTWRIGHT/CBS)

Lorre is the guy behind the current CBS comedies “Two and a Half Men,” “The Big Bang Theory” and “Mike & Molly.”

CBS is looking to shore up its comedy stable. Its Monday comedies have taken a ratings hit against NBC’s “The Voice” (moving “Men” out of that night didn’t help, either); its new comedy “Partners” already is canceled; and the future of its only other new comedy for this season, “Friend Me,” looks dubious after the death of a co-creator.

Then there’s “HIMYM,” on which many contracts will run out at the end of this season. CBS suits have made clear their hope to bring back the show in the fall.

Meanwhile, Lorre’s new comedy — about the newly sober mom living in Napa — takes him back to dangerous territory: sitcoms that have female leads.

Lorre’s the guy who famously cut his teeth on “Roseanne,” then developed comedies for Brett Butler and Cybill Shepherd, and summed it all up to Entertainment Weekly by saying, “All that toxicity, ugliness and anger was the reason to create a character like [‘Dharma & Greg’s’] Dharma.’’