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The tally of known coronavirus cases in the District, Maryland and Virginia stood at 781 on Tuesday after Maryland reported an additional 61 cases Tuesday, bringing the state’s total to 350. Virginia reported 36 more cases Tuesday for a total of 291. The District reported 21 new patients Monday, bringing its total to 141.

Here are some of the most significant and recent developments as the region responds to the pandemic of the novel coronavirus that causes the disease covid-19:

• Early Tuesday, Virginia Beach health officials said a man in his 70s with underlying health conditions had died from the virus. Later in the day, Henrico County officials announced that two people — both elderly residents of the Canterbury Rehabilitation and Healthcare Center — had also died, bringing Virginia’s total to nine.

• Maryland announced a fourth person has died of coronavirus in the state — a Prince George’s County man in his 60s who had underlying medical conditions.

• Tuesday night, D.C. announced it’s largest single-day increase in cases to date: 46, bringing the total to 187.

• D.C. Mayor Muriel E. Bowser (D) said ordered nonessential businesses to close starting at 10 p.m. Thursday. They include nail salons, barbershops, tattoo parlors and tanning salons (see a more complete list in the post below).

• Bowser said it’s possible the city will join Virginia in closing schools for the rest of the academic year, but no such decision was imminent, according to four council members who were on a call with the mayor. The mayor said she and her health department are monitoring coronavirus data and measuring whether containment measures are working before making that call.