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The number of known coronavirus cases in the District, Maryland and Virginia was 21,579 on Friday, with 11,578 cases in Maryland, 7,521 in Virginia and 2,480 in the District. The number of virus-related deaths was 499 in Maryland, 233 in Virginia and 86 in the District, for a total of 818 fatalities.

Here are some of the most significant, recent developments as the region responds to the pandemic of the novel coronavirus, which causes the disease covid-19:

• D.C. Mayor Muriel E. Bowser (D) announced Friday that school buildings will remain closed through the academic year and instruction will end late next month, rather than June 19. In Maryland, officials announced that schools will remain closed through May 15.

• The total number of covid-related deaths surpassed 800 in the District, Maryland and Virginia on Friday as case numbers reached 21,579.

• Maryland Gov. Larry Hogan (R) said Friday he expects the surging caseload of coronavirus patients to peak and start to decline soon, a key turning point in plans to reopen the state economy.