Joe Biden announced Tuesday that he has chosen Sen. Kamala D. Harris as his running mate, putting a woman of color on a presidential ticket for the first time.

The senator from California and former state attorney general had also made a run at the Democratic presidential nomination. It is only the fourth time a woman has been on a major-party presidential ticket, and Harris, the daughter of Indian and Jamaican immigrants, is the first Black and Asian American woman chosen.

The two are scheduled to appear together Wednesday in Wilmington, Del.