A police chase on Interstate 66 on Saturday afternoon left six people injured with two in serious condition, including the driver. The chase, which ended in a crash involving three vehicles, blocked eastbound traffic until nearly 6 p.m., authorities said.

The incident began shortly before 3 p.m., when police stopped a Dodge Charger for driving on the shoulder of the road, according to Corinne Geller, a spokeswoman for the Virginia State Police. The driver, Ericka S. Oliver, 25, had an outstanding warrant. As she was taken into custody, the passenger, Anthony G. McCrae, 33, drove off and was pursued by police.

Geller said police followed McCrae onto Route 123 and back onto I-66 heading east before apprehending him when his path was blocked by traffic near Sycamore Street in Arlington. McCrae hit a Ford Expedition carrying two adults and a Subaru Outback with three men in it before he was arrested and taken to Virginia Hospital Center in Arlington with serious, but non-life threatening injuries, she said.

Four of the victims suffered minor injuries and were treated at the scene. The fifth suffered serious injuries and also was taken to Virginia Hospital Center, Geller said.

McCrae is being held on outstanding warrants from Arlington and Prince William counties, with additional charges pending after Saturday’s crash. Oliver was taken into custody without incident and is being held at the Fairfax County Detention Center.