Carl Kupfer, 83, director of the National Eye Institute at the National Institutes of Health from 1970 to 2000, died April 7 at the Hebrew Home of Greater Washington in Rockville. She had pneumonia.

From 1991 to 1992, Dr. Kupfer was the acting deputy director of NIH’s Office of Intramural Training and Education. From 1982 until 1990, he was president of the International Agency for the Prevention of Blindness.

Carl Kupfer, a native of Brooklyn, N.Y., graduated from Yale University in 1949 and received a medical degree from Johns Hopkins University in 1952. He served in the Air Force from 1954 to 1956.

Earlier in his career, he was an ophthalmology instructor at Harvard University and chairman of the ophthalmology department at the University of Washington’s medical school in Seattle.

He moved to the Washington area in 1970 and had lived in Rockville since 1978.

His honors included the Presidential Rank Award.

He was a member of the Cosmos Club, American Physiological Society, Johns Hopkins Society of Scholars and the American Academy of Ophthalmology.

His marriage to Audrey Kupfer ended in divorce. His wife of 39 years, Muriel Kaiser-Kupfer, died in 2008.

Survivors include two children from the second marriage, Charles Kupfer of Camp Hill, Pa., and Sarah Kupfer of Rockville; a brother; and four grandchildren.

— Lauren Wiseman