Brent L. Chambers, 74, a retired senior officer of the CIA’s Directorate of Intelligence, died March 8 at Mount Vernon Nursing & Rehabilitation Center in Alexandria. He had cancer.

The death was confirmed by his wife, Lynn Chambers.

Mr. Chambers joined the CIA in 1962 and retired in 1993 as a senior inspector on the inspector general’s staff. During his career, he led the CIA’s multidisciplinary Cuba analysis center. His honors included the Career Intelligence Medal.

Brent Leon Chambers was a native of Fort Scott, Kan., and a 1960 graduate of the University of Nebraska, where he also received a master’s degree in international studies and political science in 1962. The CIA sponsored him for year-long sabbaticals at Stanford University and then at the Royal College of Defense Studies in London.

In retirement, he was a volunteer and docent at the U.S. Holocaust Memorial Museum in Washington and a Democratic Party volunteer. His avocations included long-distance walking on many trips to Scotland, England and France, including the 190-mile trek across northern England. He was an Alexandria resident.

His first marriage, to Mary Elizabeth Randles, ended in divorce.

Survivors include his wife of 27 years, Lynn Scapes Chambers of Alexandria; three children from his first marriage, Diane Yates of Waterford, Va., Douglas Chambers of Hattiesburg, Miss., and Kevin Chambers of Delray Beach, Fla.; and two grandchildren.

— Adam Bernstein